The Injectable Estradiol and Progesterone Shortages of 2018

MTF Trans Hormonal Therapy

Rev. 6, by Beverly Cosgrove, 9-6-2018

UPDATE 9-9-2018: Perrigo states that there is a limited supply of the 40mg/ml generic available. Perrigo also forecasts that the 20mg/ml generic will become available this month, in September.

UPDATE 6-26: (1) Perrigo has declared, finally, an official shortage, but confirmed that they intend to CONTINUE production of EV in 20mg/ml and 40mg/ml strengths. Their announcement says “Perrigo has estradiol valerate 20 mg and 40 mg vials on back order and the company estimates a release date of August 2018.” (2) A new shortage of Estradiol Cypionate injection in the Los Angeles area has been reported by patients. (3) One patient in Sweden has reported a shortage of Polyestradiol Phosphate (Estradurin).


Once again, shortages of injectable estradiol have appeared. AMAB trans women who are entirely dependent on injected estradiol are finding that their usual prescription is entirely unavailable. And a sense of panic is…

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